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Forskolin Review: Is This Product a Miraculous Natural Remedy?

Coleus forskohlii is one of the herbs on the power of which Ayurvedic medicine relies. Recently, this herb has become a tool, helping get rid of excessive weight.

The extract derived from the herb is now an irreplaceable ingredient in many supplements. The name of this ingredient is Forskolin. The supplements which contain it help regulate testosterone levels, as well as have anti-inflammatory and anti-cancer effects.

Notwithstanding existing evidence concerning Forskolin efficacy, a greater number of studies have to be conducted. The majority of studies involving this substance were carried out not inside the body. It means that inside the body the effect can be unpredicted.

Forskolin is known for its ability to boost the production of cyclic adenosine monophosphate. The increase in cAMP levels promotes the decrease in fat percentage and the enhancement of other weight-loss ingredients’ effects.

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Forskolin 250

A few researches in human subjects have shown a potential to help fix excessive weight problem. The study in women with excessive weight has indicated that Forskolin can be effective for preventing further weight gain. For this purpose, the female participants took 250 mg of supplement, containing 10% Forskolin extract twice a day.

Another study, involving men with excessive weight, lasted for 12 weeks. The participants underwent supplementation, taking the same dose as the women from the previous study did. As a result, the men experienced the improvement of body composition.
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Forskolin is a unique naturally occurring substance that has a strong potential to cure a wide range of disorders, including testosterone deficiency, skin diseases, cardiac accident, respiratory system diseases, and even cancer.
The roots of plant Coleus Forskohlii is a source of Forskolin. This compound is actually an extract available in a number of supplements. Pure Forskolin is widely used as a part of anti-obesity therapy since this substance has the ability to promote weight loss. But it’s worth noting that some famous people, for example Dr. Oz overestimate the body weight-reducing potency of this natural compound. The application of this compound still can be very favourable as an auxiliary weight-loss tool that perfectly complements high intensity workout programs and well-balance diet plans.
There are the top-notch pure Forskolin-containing products made by the trustworthy manufacturers. It’s a security matter to purchase the supplement from the manufacturer or supplier with flawless reputation to make sure you don’t use a dangerous counterfeit product. It’s possible to purchase such products from the legitimate healthcare providers. There are also the official retailers who sell the supplements of superior quality on the Internet.
But before you decide to try the real power of Forskolin for getting rid of undesirable pounds, it’s recommended to visit the healthcare practitioner. In addition, learn as much information about this supplement as possible. In such a way, you will know how to use the natural efficacy of this active substance with the greatest benefit for your body weight and overall well-being.


According to the results of studies in cats, coleus forskohlii, when taken orally, features a high absorption rate in the digestive tract. In rats, the substance features a high absorption rate in the intestinal tract and large bowel. But still the greatest efficiency of absorption is typical for duodenum.
Forskolin undergoes P-glycoprotein intestinal efflux. When P-glycoprotein inhibitor is congested, oral administration of the substance may become even more beneficial.

Toxicity Level

Toxicity level of coleus forskohlii is not high. But the supplement can stimulate acid secretion in the stomach. The patients with stomach ulcer should avoid supplementation since it may be harmful for them.


Aortic cells typically enhance calcium absorption as a reaction to the influence of cAMP. However, the process of incubating Forskolin for 20 hours may decrease the effects of cAMP exposure on these cells. This incubation still doesn’t affect the sensitivity of adenylate cyclase. As a result, it’s possible to boost refractory adaptation. In other cells, refractoriness depended on protein synthesis. Isoproterenol can imitate the development of refractoriness.

The Truth by Dr. Oz

I don’t have the problem with excessive weight and my BMI is more than suitable. However, I regularly receive hundreds of advertisements that try to persuade me in the existence of miraculous anti-obesity supplements. Usually, these supplements are recommended by Dr. Oz. Earlier, I have already reviewed Garcinia cambogia claimed to be the latest weight-loss development. At that time, I was sure that Dr. Oz would soon bring the new product to our attention. And that really happened. Thus, advertisements of Forskolin, the innovative weight-loss pills, quickly replaced the advertisements of Garcinia cambogia.

Repeatedly, Dr. Oz demonstrated how Forskolin burns belly fat. During one of his shows, he impressed the audience with a fat belly paper model that was burnt off to make people know how powerful Forskolin is. When paper disappeared in the twinkling of an eye, muscle tissue model has become visible. According to Dr. Oz, that’s how Forskolin destroys fat – rapidly and effectively.

Also, Dr. Oz invited a dietitian to another show in order the audience could hear the competent opinion of the professional regarding the new anti-obesity pills. The specialist told that her clients took Forskolin and lost 100% more pounds that without this supplementation. However, she brought to notice that people with excessive weight shouldn’t solely rely on the supplement effects. It means that nobody negated the need for a well-balanced diet and workouts.

Dr. Oz claims that the studies support the use of Forskolin as the metabolism activator. He compares the supplement effect on the metabolism to the powder that makes water boiling faster and more intensely.

The Truth by Science

In fact, Dr. Oz likes to back his arguments with scientific evidence. The same is with Forskolin 250. Thus, he tells about the study in which only 30 male participants took part. The duration of the study was 12 weeks. The first group consumed the supplement, while the second group was a placebo one. Men who underwent supplementation experienced the improvement in body composition. It means that fat percentage and fat mass have dropped substantially. In addition, according to www.naturaltestosteronepills.com bone mass and lean body mass have slightly grown. Moreover, a considerable elevation of free testosterone levels was also noticed. Notwithstanding these generally positive results, the supplementation didn’t cause weight changes. However, body composition improvement was obvious. As for the increase in T levels, it can even negatively affect the men’s health if these levels were initially normal. So, based on the study results, it’s not reasonable to state that the supplement burns fat and makes people lose weight.

The second study involved 23 female participants with mild obesity. At the end of the study, the body composition in women remained unchanged. The body weight also didn’t decrease. So, the scientists found out that women can’t lose weight by taking Forskolin. But at the same time, they state that the supplement can prevent further weight gain in women. The supplementation didn’t cause dangerous adverse effects.

In the above-mentioned studies, humans took part. And there were no other studies, involving humans. Just one study can really give evidence that Forskolin can help cope with excessive weight caused by overeating. But that was the animal study; that is, the study in rats.

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What Forskolin Is

Forskolin is a chemical compound which has a natural origin. It’s possible to obtain it from Coleus forskohlii plant. It acts by directly influencing cAMP levels responsible for heart muscle function. As for the other effects of this substance, they lack scientific support. Thus, there is the hypothesis that the supplement activates thyroid gland and takes part in prevention of platelet aggregation. There are also claims that Forskolin can impede cancer tumor growth and inhibit metastatic spread. However, sufficient clinical trials have not been conducted in order to confidently tell that the supplementation really can be used for treatment and it will not result in serious side effects.

Moreover, studying the information that the Natural Medicines Comprehensive Database gives, it’s possible to get to know that Forskolin is considered to be “possibly effective”. But even this classification is not related to weight loss. Thus, the Database indicates that this chemical compound might be used for treating idiopathic congestive cardiomyopathy and asthma. There is also a supposition that Forskolin can lower eye pressure. Nevertheless, clinical trials with the involvement of people suffering from glaucoma have not been carried out yet. In addition, it’s worth mentioning that according to the above-mentioned Database, Forskolin is “possibly safe”. In particular, the risk of drug interaction exists. That’s why it’s dangerous to combine this supplement with prescription medications, herbs, and other supplements. Also, there are the grounds for believing that Forskolin supplementation can cause bleeding. For this reason, the patients must stop supplementation 2 weeks before the planned surgery.

What Is in Reality?

After studying the existing facts about Forskolin, I drew certain conclusions:

  • The principle of Forskolin action is quite convincing based on the study findings.
  • There is only one study showing the positive effect of the supplement on body composition.
  • The studies haven’t proven the weight loss effect of the supplement. Only the study in rats gives a slight evidence of such an effect.
  • Reasonability and safety of the supplement use remain doubtful.
  • The supplement contributes to the increase in testosterone levels. But this effect is questionable.

I don’t argue that Forskolin is completely ineffective for overweight or obese people. However, we still don’t have appropriate study findings, proving that it really promotes weight loss. Also, I don’t mean the supplementation is dangerous for people. But people shouldn’t believe that the supplement is completely harmless. I’m just trying to appeal for everyone who is going to take the supplement to think critically instead of solely trusting the opinion of Dr. Oz and his supporters. And by the way, it’s highly improbable that Dr. Oz would call the newly developed prescription medication very effective and safe without the positive results of the numerous large-scale clinical trials.

Allergic Symptoms Relief

Forskolin is long famous for its high potential to relieve symptoms of different allergic conditions. According to the study findings, Forskolin is one of the natural substances which can substantially reduce the allergen concentrations in blood when anaphylactic reaction happens. In particular, it was proven that this compound makes the walls of vessels less permeable.
Forskolin can also make the airways of the lungs wider. Due to this fact, the substance is very beneficial for curing asthma and the other diseases of respiratory system. The clinical trial has indicated that the frequency of asthma attacks in the patients decreased by 45% after 8-month Forskolin supplementation. The participants took 10 mg of this natural compound every day during the whole study period.

Heart Support

The animal studies have demonstrated that Forskolin takes an active part in restoring heart tissues, which suffer from cardiac insufficiency. The substance also boosts the activity of myocardial adenylate cyclase, which is a very important enzyme for proper heart functioning. Thus, this enzyme is available in the heart tissues. The lack of this enzyme will cause dangerous cellular problems in the heart tissues. Forskolin prevents this situation. Due to the intake of this substance, it’s possible to improve heart rate and dilate blood vessels. That’s why the doctors even prescribe Forskolin for treating congestive cardiomyopathy. But of course, such treatment is possible only under medical supervision.

Ever-Repeating Story

The new developments in the weight-loss supplement industry disappoint but, at the same time, don’t surprise me. That’s because the story hasn’t changed since my review of Akavar 20/50, the manufacturer of which claimed that it’s possible to eat everything and get rid of unwanted pounds. Thus, each time, while having no trustworthy clinical trials results, the manufacturers exaggerate the efficacy of their products and use aggressive marketing strategies. Of course, you can always find honest feedback from people whom the particular supplement helped overcome overweight. Well, most probably that happens not because of the magical anti-obesity pills effects but because of decreased food intake and high-intense workouts. But then the manufacturers launch the new weight-loss product, and Dr. Oz advertises it. Therefore, these people switch their attention to another supplement, promising more amazing weight-loss results. And everything is repeating again and again. I want everyone who wants to use the weight-loss supplements to check all available scientific evidence about a certain product before consuming it, instead of mistaking the wish for the reality. Definitely, healthy skepticism is always useful. And it’s especially true when it comes to making decisions on which your health depends.

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How Forskolin Contributes to Weight Loss

Decreases the feeling of hunger

Food gives you energy. But the excessive food intake always leads to the weight gain. If you manage to reduce food cravings, you can eat less. The energy expenditure will be greater than energy intake. This will cause calorie deficit. The calorie deficit is a necessary condition for the effective weight loss.

Boosts metabolic rate

Slow metabolism leads to the formation of fat deposits and the increased body weight. But if you accelerate your metabolism, you will also trigger the fat burning mechanism. The decrease in body fat percentage will beneficially change your body composition.

Decreases food assimilation

Food that you consume passes a long way in the gastrointestinal tract till your body cells get building material and energy; that is, till the food is assimilated in your body. But a calorie surplus makes you gain unwanted pounds. The decrease in food assimilation prevents this situation and promotes weight loss.

Eliminates fatigue

Fatigue during workouts is a widespread issue because of which many people don’t want to do workouts. Since Forskolin reduces and prevents fatigue, you will have an opportunity stick to your workout plan more successfully and develop bigger muscles.

The Verdict

Forskolin is considered a well-working dietary supplement. Different studies have confirmed its ability to enhance metabolism, regulate energy expenditure, and melt fat. It’s also known that this natural product is effective for solving acne problem, curing asthma, improving blood circulation, and fighting depression. And it’s not the full list of its possible uses.
It’s worth noting that the lifestyle changes are most crucial for warding off weight gain and ensuring weight loss. Take care of the healthy diet plan first of all. Try to avoid overeating and don’t consume junk foods. The well thought-out workout plan is also crucial. If you take these steps, you will be able to shed unwanted pounds and maintain normal body weight. Also, you will get many additional health benefits. It’s necessary to renew lifestyle regardless of whether you are going to take dietary supplements or not. But if you aspire to get the most satisfying weight loss results, you should combine supplementation with proper nutrition plan and professional workout program.
If you are planning to take Forskolin to get rid of excessive weight, you have to choose only the top-notch product. The supplement should contain 20% of completely pure Forskolin extract. There should be no additives, binders, and fillers. In such a way, you will guarantee own safety and reach your weight loss goals.

Is Forskolin Available in Foods?

There is only one known source of Forskolin. And it’s an herb, not foods. Moreover, scientific proof of Forskolin efficacy applies to the root extract only. The efficacy and safety of the other parts of herb have not been investigated.

Adverse Effects

People who have no medical conditions usually don’t suffer from any Forskolin adverse effects. But still the list of possible adverse effects includes hypotension, headache, and racing heart. Forskolin is also known for its ability to stimulate gastric acid secretion. That’s why for the patients with ulcer it’s not recommended to use this extract. Forskolin is also not suitable for the patients with diabetes since the extract promotes the elevation of glucose levels and has an impact on the release of lipids.


Women should avoid Forskolin during pregnancy and breastfeeding. The studies proving that the extract is not harmful for these women have not been conducted yet. You shouldn’t take Forskolin if you are now taking vasorelaxants, antithrombotic drugs, beta adrenergic blocking agents, and calcium channel inhibitors. Consult the healthcare practitioner before starting supplementation to ensure own safety and prevent any complications.

Clinical References
1. https://www.ncbi.nlm.nih.gov/pubmed/22393824
2. https://www.news-medical.net/?tag=/Weight-Loss